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Francesco Amenta Selected Research

Glycerylphosphorylcholine (Choline Alfoscerate)

1/2022Association Between the Cholinesterase Inhibitor Donepezil and the Cholinergic Precursor Choline Alphoscerate in the Treatment of Depression in Patients with Alzheimer's Disease.
1/2017The Effect of the Association between Donepezil and Choline Alphoscerate on Behavioral Disturbances in Alzheimer's Disease: Interim Results of the ASCOMALVA Trial.
1/2014The ASCOMALVA (Association between the Cholinesterase Inhibitor Donepezil and the Cholinergic Precursor Choline Alphoscerate in Alzheimer's Disease) Trial: interim results after two years of treatment.
12/2013Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phospholipid with a still interesting profile as cognition enhancing agent.
2/2013Modulation of monoaminergic transporters by choline-containing phospholipids in rat brain.
11/2012The ASCOMALVA trial: association between the cholinesterase inhibitor donepezil and the cholinergic precursor choline alphoscerate in Alzheimer's disease with cerebrovascular injury: interim results.
8/2009Neuroprotective effect of treatment with galantamine and choline alphoscerate on brain microanatomy in spontaneously hypertensive rats.
6/2007Cholinergic precursors in the treatment of cognitive impairment of vascular origin: ineffective approaches or need for re-evaluation?
11/2006Effect of treatment with choline alphoscerate on hippocampus microanatomy and glial reaction in spontaneously hypertensive rats.
10/2002The cholinergic approach for the treatment of vascular dementia: evidence from pre-clinical and clinical studies.

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Francesco Amenta Research Topics

Disease

16Cognitive Dysfunction
01/2021 - 03/2002
15Hypertension (High Blood Pressure)
06/2021 - 01/2002
14Alzheimer Disease (Alzheimer's Disease)
01/2022 - 05/2004
11Dementia (Dementias)
07/2021 - 10/2002
7Obesity
03/2022 - 01/2017
7Gliosis
01/2021 - 05/2004
6Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy)
01/2012 - 10/2002
5Stroke (Strokes)
02/2013 - 04/2006
4Hypertrophy
04/2022 - 04/2003
4Inflammation (Inflammations)
04/2021 - 01/2017
4Pain (Aches)
01/2021 - 01/2014
4Cerebrovascular Disorders (Cerebrovascular Occlusion)
12/2013 - 11/2006
3COVID-19
12/2021 - 01/2020
3Neurobehavioral Manifestations
03/2013 - 11/2006
2Hypersensitivity (Allergy)
12/2021 - 04/2018
2Fibrosis (Cirrhosis)
06/2021 - 04/2003
2Body Weight (Weight, Body)
05/2020 - 01/2020
2Type 2 Diabetes Mellitus (MODY)
01/2020 - 06/2007
2Neurodegenerative Diseases (Neurodegenerative Disease)
11/2017 - 03/2013
2Asthma (Bronchial Asthma)
07/2015 - 08/2002
2Ischemic Stroke
08/2009 - 11/2008
2Essential Hypertension
11/2007 - 11/2002
2Coronary Disease (Coronary Heart Disease)
04/2006 - 05/2004
2Necrosis
05/2004 - 04/2003
1Wounds and Injuries (Trauma)
03/2022
1Nervous System Diseases (Neurological Disorders)
11/2021
1Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
06/2021
1Cardiovascular Diseases (Cardiovascular Disease)
04/2021
1Hyperlipidemias (Hyperlipidemia)
03/2021
1Low Back Pain (Lumbago)
01/2021
1Neuroinflammatory Diseases
01/2021
1Gingivitis
11/2020
1Hemorrhage
11/2020
1Infections
11/2020
1Varicose Veins (Varicose Vein)
08/2020
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2019

Drug/Important Bio-Agent (IBA)

21Cholinergic Agents (Cholinergics)IBA
03/2022 - 03/2002
10Glycerylphosphorylcholine (Choline Alfoscerate)IBA
01/2022 - 10/2002
9Cholinesterase Inhibitors (Anticholinesterases)IBA
01/2022 - 02/2006
7AntioxidantsIBA
06/2021 - 02/2013
7Thioctic Acid (Lipoic Acid)IBA
06/2021 - 01/2013
71,4-dihydropyridine (dihydropyridine)IBA
11/2008 - 01/2002
5Proteins (Proteins, Gene)FDA Link
04/2022 - 05/2004
5Donepezil (Aricept)FDA LinkGeneric
01/2022 - 11/2012
5Cholinergic ReceptorsIBA
07/2015 - 03/2002
5Antihypertensive Agents (Antihypertensives)IBA
08/2009 - 11/2002
5Nicardipine (Dagan)FDA LinkGeneric
08/2009 - 10/2002
4Reactive Oxygen Species (Oxygen Radicals)IBA
05/2021 - 08/2011
4Glial Fibrillary Acidic ProteinIBA
01/2016 - 10/2002
4Choline (Choline Chloride)IBA
01/2015 - 06/2007
4Cytidine Diphosphate Choline (Citicoline)IBA
03/2013 - 10/2002
4Pharmaceutical PreparationsIBA
08/2009 - 11/2002
3CholesterolIBA
01/2020 - 04/2006
3Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
01/2008 - 03/2002
3lercanidipineIBA
06/2007 - 10/2002
2Nucleic AcidsIBA
06/2021 - 01/2016
2CytokinesIBA
04/2021 - 10/2005
2PhytochemicalsIBA
03/2021 - 01/2020
2Insulin (Novolin)FDA Link
05/2020 - 01/2020
2Superoxide DismutaseIBA
03/2020 - 01/2019
2Triglycerides (Triacylglycerol)IBA
01/2020 - 01/2017
2PolyphenolsIBA
01/2020 - 09/2018
2Acetylcholine (Acetylcholine Chloride)FDA Link
01/2015 - 06/2007
2Neuroprotective AgentsIBA
12/2013 - 05/2004
2Phospholipids (Phosphatides)FDA LinkGeneric
02/2013 - 06/2007
2Memantine (Namenda)FDA Link
01/2013 - 01/2012
2Nimodipine (Modus)FDA LinkGeneric
11/2008 - 10/2002
2Phosphatidylcholines (Phosphatidylcholine)IBA
06/2007 - 11/2006
2CalciumIBA
06/2007 - 07/2004
2Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
07/2004 - 11/2002
2DiureticsIBA
07/2004 - 11/2002
2Hydralazine (Apresoline)FDA LinkGeneric
10/2002 - 01/2002
2Vasodilator Agents (Vasodilators)IBA
10/2002 - 01/2002
1Hyaluronic Acid (Hyaluronan)IBA
12/2021
1VaccinesIBA
12/2021
1BNT162 VaccineIBA
12/2021
1Dermal FillersIBA
12/2021
1Ion Channels (Ion Channel)IBA
11/2021
1Oxidants (Oxidizing Agents)IBA
05/2021
1LeptinIBA
04/2021
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2021
1Interleukin-6 (Interleukin 6)IBA
04/2021
1FlavonoidsIBA
03/2021
1Vesicular Acetylcholine Transport Proteins (Vesicular Acetylcholine Transporter)IBA
01/2021
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
01/2021
1remdesivirIBA
09/2020
1Antiviral Agents (Antivirals)IBA
09/2020
1Glycerol (Glycerine)FDA LinkGeneric
08/2020
1Lidocaine (Xylocaine)FDA LinkGeneric
08/2020
1Sodium Salicylate (Salicylate, Sodium)IBA
08/2020
1SolutionsIBA
08/2020

Therapy/Procedure

4Therapeutics
01/2021 - 10/2002
2Injections
12/2021 - 08/2020
2Ligation
01/2021 - 04/2018
2Drug Therapy (Chemotherapy)
01/2019 - 03/2011
2Activities of Daily Living (ADL)
11/2012 - 11/2012
1Precision Medicine
07/2021
1Oral Hygiene (Dental Hygiene)
11/2020
1Patient Isolators (Life Island)
11/2020
1Personal Protective Equipment
01/2020